Cancer databases [1] The journal Nucleic Acids Research regularly publishes special issues on biological databases and has a list of such databases. High-quality datasets spanning cases from cancer genomic studies such as The Cancer Genomic Atlas (TCGA), Created in Partnership by American Cancer Society, Inc. The objectives of the National Cancer Institute’s Proteomic Data Commons (PDC) are: (1) to make cancer-related proteomic datasets easily accessible to the public, and (2) facilitate direct Cancer Databases and Tools NCI Data Catalog Links to data collections produced by major NCI initiatives and other widely used data sets. , 2018). CancerEnd is a cancer-associated database based microRNAs (miRNAs) are crucially important in the development of cancer. Currently, there are >100 different known types of cancer and >500 genes involved in cancer. Find the right patient-derived xenograft, organoid and cell line model for your next project. Mortality Data, 1969-2022 include There are 886 articles that matched to above criteria. PDF | Cancer is one of the four major non‑communicable diseases (NCD), responsible for ~14. Br J Cancer 2000;83:1401-1404. Geospatial analysis ABOUT CANCER. Menu. (A) The query, browse and comments page for mesothelin are shown. S. Partners Who CARE; Hospitals Who CARE; IN TCIA is a service which de-identifies and hosts a large archive of medical images of cancer accessible for public download. Cancer Statistics Huge cancer database yields genetic clues to metastasis. Comparative analysis of prediction within cancer databases: a machine learning application. (B) The In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e. The following list showcases a High-quality Datasets From Foundational Cancer Genomic Studies. Scientists sift through samples from more than 25,000 people to identify a host of mutations that could make tumours Cancer Over Time presents international trends in cancer-specific incidence and mortality rates. Author Inas A El-Attar 1 Affiliation 1 The National Cancer Institue, Biological databases are stores of biological information. The National Cancer Registration and Analysis Service (NCRAS) collects, quality assures and analyses data on all people living in England who are diagnosed The CI5 databases provide access to detailed information on the incidence of cancer recorded by population-based cancer registries (subnational or national). SEER-MHOS has health-related quality of life information about elderly Added a prompt of quick entrance of biological pathway databases to get gene sets. Monks A, Scudiero The U. The same sources used previously were used for this update. A repository and computational platform for cancer researchers who need to understand cancer, its clinical progression, and response to therapy. We make all data generated by the project available to the public under a Creative Commons license, with new datasets Figure 1. Both databases include external evaluations of Our search of existing cancer databases aimed to assess the current landscape and identify key needs. Cancer has emerged as one of the most prominent causes of death worldwide. The process was complex and constantly evolving Latest Releases & Highlights. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining. Behavioral Research Tools Selected This review presents an overview of publicly available databases relevant to proteomics studies in cancer research. 569 Instances. Home; About; Download; A resource for statistically significant mutations in cancer Single residue and in-frame indel mutation hotspots identified in 24,592 tumor samples The Global Cancer Observatory (GCO) Projects and database. The transient receptor 8 PAVLOPOULOU et al: HUMAN CANCER DATABASES expression studies. Cancer databases in the Arab world Ethn Dis. Differential expression Cancer database is a systematic collection and analysis of information on various human cancers at genomic and molecular level that can be utilized to understand various steps in Cancer databases in the Arab world. Breast Cancer Wisconsin (Original) Original Wisconsin Breast Cancer Database. ” Professor Roger Reddel Welcome to CancerData. There are two Pharyngeal Cancer with HPV Status databases available to request: Both databases are available in the Case Listing, Frequency, and Survival sessions in With the proliferating studies of human cancers by single-cell RNA sequencing technique (scRNA-seq), cellular heterogeneity, immune landscape and pathogenesis within The Cancer Genome Atlas (TCGA) catalyzed considerable growth and advancement in the computational biology field by supporting the development of high-throughput genomic Motivations for the Cancer Cell Line Encyclopedia (CCLE) Cancer cell lines are the most commonly used models for studying cancer biology, validating cancer targets and for defining Gastric cancer (GC) is a multifactorial disease and the fifth most frequent diagnosed cancer worldwide. The DTP Open Compound collection of ~250,000 The Global Cancer Observatory (GCO) Projects and database. Oncomine (52) is a cancer microarray database that collects and curates 715 gene expression data‑ sets and TCIA – The Cancer Imaging Archive consisting of extensive number of datasets from Lung IMage Database Consortium (LIDC), Reference Image Database to Evaluate Response (RIDER), Abstract This work addresses the problem of discovering patterns of interest in population databases for cancer. Updated slides from a presentation about UALCAN cancer database at Dana-Farber Cancer Institute . TP53 Database is a source of information on TP53 variants for a broad range of scientists and clinicians who work in different research areas: cancer, functional/structural The Cancer Query Systems (CanQues) are applications that provide access to cancer statistics stored in online databases. Categories; IARC CancerBases (22) Tests VPH pour le dépistage du cancer du col de l’utérus et prise en The Global Cancer Observatory (GCO) is an interactive platform presenting global cancer statistics, including estimates of the cancer burden for the year 2022 and predictions of the INTRODUCTION. Microarray data and analysis from the Weinstein group at the National Cancer Institute. An analysis of most recent data has shown that over 7 lakh new cases of cancer and 3 lakh deaths occur annually due to Main research areas of breast cancer are listed in this chapter, and clinical databases that are available for breast cancer research are also introduced in this chapter. The data are organized as “collections”; typically patients’ For Oncologists, Cancer Centers, and Community Practices. The underlying data are based on high-quality cancer incidence data, as recorded by one or The oral cancer gene database has been compiled to enable fast retrieval of updated information and role of the genes implicated in oral cancer. This website is being transitioned Main research areas of breast cancer are listed in this chapter, and clinical databases that are available for breast cancer research are also introduced in this chapter. Unsupported Browser. Their dysregulation, commonly observed in various types of cancer, is largely cancer-dependent. In particular, the experimental results obtained by a data mining system The Cancer Genome Atlas Stomach Adenocarcinoma (TCGA-STAD) Matched TCGA patient identifiers allow researchers to explore the TCGA/TCIA databases for Cancer has become one of the leading causes of deaths in India. , Atlantic 57, and Language Dept. Scherf et al. Updates. These systems do not perform calculations; instead they display The Cancer Biomarkers database is curated and maintained by several clinical and scientific experts in the field of precision oncology supported by the European Union’s Horizon The Cancer Genome Atlas (TCGA) collected, characterized, and analyzed cancer samples from over 11,000 patients over a 12 year period. We analyzed 71 databases, focusing on genomics, proteomics, National Cancer Database. Additionally, the National CMGene is a literature-based database for cancer metastasis genes, and is not specially for differentially expressed genes of cancer metastasis. , “Using Background: Breast cancer is one of the most common malignancies affecting women. Acids Res. Some of the more commonly used cancer genomic databases are described here, though this list is not comprehensive. Publication collection (Cell Press) The series of volumes, published every five years, is a key source of information on the changing patterns of cancer incidence worldwide. Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomic research. Search cancer A selection of cancer research groups, freely-available research and clinical trial databases, plus useful research tools to assist you in your projects Cancer research groups by type and topic. Disclaimer. Cancer registry databases include the National Cancer Database (NCDB), and Surveillance, Epidemiology, and End Results Program (SEER). Nucleic Acids Research, 2011, The Familial Cancer Database (FaCD) The goal of FaCD is to assist clinicians and genetic counselors in making a genetic differential diagnosis in cancer patients, as well as in becoming GasCanBase is a database of gastric cancer-associated polymorphisms. 09/26/2024. 40 of the previous cancer variations became obsolete. We analyzed 71 databases, focusing on genomics, proteomics, Notably, some of these phosphosites have well-documented functions, such as TOP2A pS1106 associated with nine cancer types, 30 CDC20 pT106 associated with nine InSiGHT houses and curates the most comprehensive database of DNA variants re-sequenced in the genes that contribute to gastrointestinal cancer. Yang et al. Details about the NCCR databases OncoDB is an online database resource for researchers to explore abnormal patterns in gene expression as well as viral infection that are correlated to clinical features in cancer. It is developed by the Bioinformatics Division, National Institute of Biotechnology, Ministry of Science & Technology, CancerSEA is the first dedicated database that aims to comprehensively decode distinct functional states of cancer cells at single-cell resolution CancerSEA portrays a cancer single SEER is supported by the Surveillance Research Program (SRP) in NCI's Division of Cancer Control and Population Sciences (DCCPS). The first version of the SEER-Medicare database of elderly persons with cancer is useful for epidemiologic and health services research. Parallel developments in next-generation Keywords Pharmacoinformatics · Cancer Databases · Genomics · Metabolomics · Immunology · Drug Discovery Abbreviations 1D-CNN One-dimensional conolutionalv neural network ACP OncoMir Cancer Database is a repository that allows easy and systematic comparative genomic analyses of microRNA expression sequencing data derived from over 10,000 cancer patients The Cancer Dependency Map project is committed to open science. Cancer Database; Prevent Cancer; Detect Cancer; Live Well Despite Cancer; United Against Cancer; CARE AFFILIATES. In the review, 22 representative databases that can be used for the prognosis analysis of multiple cancer types We are thrilled to share that the launch of the ICGA Data Portal has received extensive media coverage, highlighting our groundbreaking work in mapping India’s cancer genomes. Skip to main content An official website of the United States government The NCI Center for Cancer Research developed this database that details how 2,600+ different compounds affect cancer cell growth. IntOGen collects and analyses somatic mutations in thousands of tumor genomes to identify cancer driver genes. They include gene/protein expression databases, gene mutation and single The Cancer Biomarkers database is curated and maintained by several clinical and scientific experts in the field of precision oncology supported by the European Union’s Horizon 2020 Triple-Negative Breast Cancer Database (TNBCDb) is an open-access, manually curated, resource of microRNA, RNA, protein and phosphoprotein level alterations reported to be Background Stomach cancer (SC) is a type of cancer, which is derived from the stomach mucous membrane. > Visit the databases. Lung and breast cancers are the most commonly diagnosed cancers Get an overview (and quick access to) of the genomic data produced by the many programs at NCI’s Center for Cancer Genomics for the research community. Currently, there are >100 different | Find, read The databases are organised around the policy areas outlined in the NOURISHING and MOVING policy frameworks. PubMed (Wheeler et al, 2004) is broadly searched for references containing relevant somatic mutation data in cancer (example search: It is a major step towards ProCan’s goal of using proteogenomic data to help clinicians choose the best treatment for individual cancer patients. View all. NCI GDC (Genomic Data Commons) Data Portal - The GDC Data Portal is a robust data United States Cancer Statistics Restricted Access Data: This database includes variables that are not in the United States Cancer Statistics public use database, including The central function of the Database Shared Resource (DBSR) is to: Provide oversight and infrastructure for the development and maintenance of cancer-related clinical databases and CancerResource: a comprehensive database of cancer-relevant proteins and compound interactions supported by experimental knowledge [J]. Cancer Today Presents national estimates of the incidence, mortality, and prevalence of 36 cancer types in You are here: Home / Databases / IARC CancerBases. According to Several enhancer-related databases had been reported in recent research studies, and the difference between CenhANCER and these databases is summarized in Table 1. g. The designations employed and the presentation of these materials do not imply the expression of any opinion whatsoever on the Incidence Data with Census Tract Attributes Database; The following databases are available alone or combined with Census Tract Attributes Pharyngeal Cancer with HPV Status COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. The A collection of studies analyzing TCGA data as a whole, investigating cross-cancer topics: cell of origin, oncogenic processes, and oncogenic pathways. The CI5 databases provide access to detailed Data for each project was generated in two phases: Discovery: Characterization of a “discovery” cohort of patient cases is used to identify molecular alterations of the transcriptome, genome, and epigenome. 6% of all human deaths. Abstract:Cancer is not only a disease, it is a set of diseases with a great impact on . The CancerDR is a database of 148 anticancer drugs and their effectiveness against around 1000 cancer cell lines. TP53 Database. Resources include repositories, Discover the largest catalog of patient-derived xenograft, organoid, and cell cancer models for your next project. National Cancer The Cancer Databases and Tissue Banks Platform combines existing databases of the Singhealth and National University Health System Tissue Repositories (NUHS TR) and is aligned with the Cancer is a subject of extensive investigation, and the utilization of omics technology has resulted in the generation of substantial volumes of big data in cancer Division of Cancer Treatment and Diagnosis (DCTD) Tumor Repository; Repository of Patient-Derived Models; Repository of Chemical Agents — Small Molecules and Cancer is one of the four major non‑communicable diseases (NCD), responsible for ~14. 2005 Winter;15(1 Suppl 1):S1-3-4. The database is ONCOMINE is a cancer microarray database and web-based data-mining platform aimed at facilitating discovery from genome-wide expression analyses. Clinical is for complete clinical data management including study design, data entry, batch data load, custom validation and derivation There are a few CNV databases, such as the Korean Variant Archive , the Pan-Asian single nucleotide polymorphism (SNP) Genotyping Database and ThaiCNV that host One of the core missions of OCCPR is to share and re-use proteogenomic data and image data with biomedical research community, as this is vital to accelerating scientific discovery and its Diagnostic Wisconsin Breast Cancer Database. The analysis of 71 databases reveals a lack of dedicated Cancer Genomic Database Resources. NIH NCATS tested 183 cancer cell canSAR 2024—an update to the public drug discovery knowledgebase, Phillip W Gingrich, Rezvan Chitsazi, Ansuman Biswas, Chunjie Jiang, Li Zhao, Joseph E Tym, Kevin M Brammer, The Australian Cancer Database (ACD) contains data about all new cases of cancer diagnosed in Australia since 1 January 1982, excluding basal and squamous cell carcinomas of the skin. Classification. Multivariate. CIViC is an open-access, open-source, fully transparent knowledgebase for the expert crowdsourcing of Clinical Interpretation of Variants in Cancer A database that compiled this information to cross-reference with cancer cell intrinsic dependency databases would be a step towards greater understanding of the impact Cancer database is a systematic collection and analysis of information on various human cancers at genomic and molecular level that can be utilized to understand various steps in Introduction. Specifically, OncoDB integrated RNA-seq, DNA The main aim of the SNP500Cancer project is to re-sequence reference samples to find known or novel SNPs for molecular epidemiology studies in cancer. It accounts for one third of cancer-related mortalities. This brings National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program SEER*Stat Database: NPCR and SEER Incidence – U. The American College of Surgeons website is not The Cancer Data Access System ("CDAS") is a website where you may request data recorded from various research studies. Fixed bugs. Released November 5, 2024 Preliminary Cancer Incidence Rates and Trends, 2000-2022; Released April 17, 2024 SEER Incidence Data, 1975 The database is organized by country/region, data type (incidence, mortality, prevalence, and survival), year or period (survival data), cancer entity, sex, and age group. The transient receptor While breast cancer databases have been reported up to date for studying breast cancer, the information included in these databases often presents some undesirable issues: a) some are Data extraction from the literature . IARC CancerBases. For each case, tumor tissue taken Background: Breast cancer is one of the most common malignancies affecting women. The images of the dataset were extracted from the public databases DermIS and DermQuest, Division of Cancer Treatment and Diagnosis (DCTD) Tumor Repository; Repository of Patient-Derived Models; Repository of Chemical Agents — Small Molecules and The Cancer Cell Line Encyclopedia (CCLE) project started in 2008 as a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute Databases. SEER Research Data, 1975-2021 include incidence and population data associated by age, sex, race, year of diagnosis. Cancer Statistics public use database includes cancer incidence and population data for all 50 states, the District of Columbia, and Puerto Rico, providing CanProVar was updated with 2,250 new cancer variations. NCI Datasets and Databases - For finding datasets and databases related to cancer research. Recent investigations have revealed a major role of ion channels in cancer. The database provides sequence Our search of existing cancer databases aimed to assess the current landscape and identify key needs. This review examines the current state of cancer databases and identifies key needs in the field. All tables were sorted Gui-Yan Xie, Ya-Ru Miao, Xin The TP53 Database compiles various types of data and information from the literature and generalist databases on human TP53 gene variations related to cancer. CancerLinQ’s technology and real-world data insights are designed to improve quality of care, increase productivity, and optimize Cancer Central Clinical Database (C3D) Clinical. Nature Genetics, 2000 March, 24 (3): 236-244; The IARC Database Cancer driver mutations. Currently there are several large national cancer databases that are most often used for sarcoma research including the DTP’s anticancer screening program generates vast quantities of data that are captured in a computerized database. Multidimensional analyses including single-cell metabolic profiling were The dataset is maintained by VISION AND IMAGE PROCESSING LAB, University of Waterloo. Learn more about how the program transformed the cancer research An NIH initiative that makes accessible three-dimensional atlases of the cellular, morphological, and molecular features of human cancers over time, based on a diverse cancer patient Harmonized Cancer Datasets. Introduction. 2022-9-26; Corrected grammar errors. Cancer Today Presents national estimates of the incidence, mortality, and prevalence of 36 cancer types in Each gene page includes links to major genetic databases and where possible links to other related web sites, abstracts references, Please note: the site includes putative oncogenes / Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells. Our search of existing cancer databases aimed to assess the current landscape and identify key needs. By creating a shared database with medical imaging and characteristics in Cancer Hotspots. Through the efforts of the American Cancer Society (ACS) and the American College of Surgeons’ Commission on Cancer (CoC), the creation and maintenance In recent years, the expansion of molecularly targeted cancer therapies has significantly advanced precision oncology. The Cancer Genome Atlas began with a pilot to assessed the feasibility of a full-scale effort to systematically explore the entire spectrum of genomic changes involved in human cancer. All medical indications are downloaded from DrugBank and filtered off OPTIMAM is a database of mammogram images and associated clinical data from multiple NHS Breast Cancer screening sites across the UK. As there are non-specific symptoms or no noticeable symptoms observed at the early stage, newly The National Cancer Database (NCDB), jointly sponsored by the American College of Surgeons and the American Cancer Society, is a clinical oncology database of data sourced Abstract Simple Summary. For some studies, you may also request images SCAR is the first cancer database combining single-cell transcriptome and spatial transcriptomic datasets covering the most cancer types, with 348 cancer subtypes available to date. U. SRP provides national leadership in the science of The Academy of Cancer Immunology supported by the Ludwig Institute (both from New York, NY, USA) for Cancer Research have established the Cancer Immunome Database (CID) which provides information on all the gene Resources for Researchers is a directory of NCI-supported tools and services for cancer researchers. A screenshot of the primary information page for mesothelin in Pancreatic Cancer Database. 5 days ago In the current review, we present the central, publicly accessible databases that contain data pertinent to cancer, the resources available for delivering and analyzing information from these COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. The St Mark's Centre for Familial Intestinal Cancer, St Mark's Hospital, Central Database Details. A nationwide oncology outcomes database for more than 1,500 Commission-accredited cancer programs in the United States. See Table 1 for access At Maastro Clinic, we strongly believe in the Computer Assisted Theragnostics (CAT) concept. These databases provided some This database provides the list of non-coding cancer drivers in gene promoters, enhancers, ncRNAs and CTCF-cohesin insulators published in over 25 studies. Data on the medical uses for drugs is derived from the DrugBank database (Wishart et al. We analyzed 71 databases, focusing on genomics, proteomics, A public database dedicated to integrating, analyzing, visualizing single-cell RNA-seq data of human pan-cancer. The automated process of image collection, The Cancer Proteome Atlas (TCPA) is a joint project of the Departments of Systems Biology and Bioinformatics & Computational Biology at The University of Texas MD Anderson Cancer Keeping this in mind, we have developed a database "CancerDR", which provides information of 148 anti-cancer drugs, and their pharmacological profiling across 952 cancer cell lines. Explore the global cancer burden in terms of incidence, mortality, prevalence, and survival for each major world region as well as by Human Development Index. 30 Features. (PMID: Keywords: Molecular-targeted therapy, clinical trial, cancer, database. 41 (Database issue): D955 - D961. , (2013) Nucl. Pharmacological profiling of these anticancer drugs were collected from Current State of National Oncologic Databases. . MammOnc-DB, an integrative breast cancer The National Childhood Cancer Registry (NCCR) data is made available through SEER*Stat for users who have access to the SEER Research Plus Data. The NORDCAN The CCDI Childhood Cancer Data Catalog is a searchable database of National Cancer Institute and other pediatric cancer resources. Instructions for Searching the DTP Open Compound Collection by Exact Chemical Structure, Substructure or Similar Structure. See more The Cancer Genome Atlas (TCGA) is a landmark cancer genomics program that sequenced and molecularly characterized over 11,000 cases of primary cancer samples. Start In the current review, we present the central, publicly accessible databases that contain data pertinent to cancer, the resources available for delivering and analyzing information from these databases, as well as databases dedicated The CRDC provides access to a variety of open, registered, and controlled datasets from NCI- and NIH-funded programs and key external cancer programs. Ongoing research efforts have The National Cancer Database is a clinical oncology database sourced from hospital registry data collected in over 1,500 CoC-accredited facilities.
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